An accurate chemical balance capable of measuring to 0.1g is needed to weigh out the necessary reactants.
Distributors of this specialized glassware (eg. reaction vessels with Quickfit necks, double-surface condensers, distillation heads, guard tubes etc) are now required to inform authorities of ‘suspicious’ purchases. It can be very helpful to know someone who has access to laboratory glassware and glassblowing skills.
The manufacture of specialised equipment in stainless steel avoids some of these difficulties. The stainless reaction autoclave used in the “Single Shot” process has been adapted from a coffee pot and modified as problems with the process were realised. The equipment now used consists of:
• • •
a stainless steel pressure reactor vessel with pressure and temperature monitor and stirring facility a stainless condenser used for reflux and solvent extraction a stainless receiving container fitted with calcium chloride guard tubes
Stages in Barbiturate Synthesis
There are 3 basic steps in the synthesis of a barbiturate Peaceful Pill: