2008 PBL Cat_mech_r.qxd:PBL Catalog.mech 11/29/07 1:50 PM Page 33
PBL offers a range of both monoclonal and polyclonal antibodies raised not bind effectively to many of the other human interferon alpha
against different interferons from various mammalian species. The subtypes. As opposed to other commercially-available antibodies, PBL’s
commonly available human interferon antibodies have been tested human IFN alpha antibodies are tested against a wide range of human
only against human IFN alpha A (IFN-α2) and, less frequently, human IFN subtypes.
IFN alpha D (IFN-α1). Antibodies reacting with these subtypes often do
Human Interferon Alpha Antibody Specificities
Antigen Clone Label Species/Isotype Catalog # Size Interferon Gene 21100 21101 21105 21110 21112 21125 21127 21129 31100 31101 31130
Human IFN-α MMHA-2 None Monoclonal mouse IgG
1
κ, neutralizing 21100-1 50 µg Human IFN-αA IFNA2 ++ ++ ++ ++ ++ ++ ——++ ++ ++
Human IFN-α MMHA-2 None Monoclonal mouse IgG
1
κ, neutralizing 21100-2 500 µg Human IFN-α2 IFNA2 ++ —+++ ++ ——++ ++
Human IFN-α MMHA-3 None Monoclonal mouse IgG
1
λ, non-neutralizing 21101-1 50 µg Human IFN-αA/D — ++ —+++++ ++ ++++ ++
Human IFN-α MMHA-1 None Monoclonal mouse IgG
1
κ, neutralizing 21105-1 50 µg Human IFN-αB2 IFNA8 —+—++ ————++
Human IFN-α MMHA-8 None Monoclonal mouse IgG
2B
κ, neutralizing 21110-1 50 µg Human IFN-αC IFNA10 +++++ — ++ ——++
Human IFN-α MMHA-11 None Monoclonal mouse IgG
1
κ, neutralizing 21112-1 50 µg Human IFN-αD IFNA1 ++ ++ + ++ ++ ++ ++ ++ —+++
Human IFN-α MMHA-13 None Monoclonal mouse IgG
1
κ, neutralizing 21116-1 50 µg Human IFN-αF IFNA21 —+————+—++
Human IFN-α MMHA-17 None Monoclonal mouse IgG
1
κ, neutralizing 21118-1 50 µg Human IFN-αG IFNA5 ++ ++ ++ ++ — ++ ++ —+
Human IFN-α MMHA-6 None Monoclonal mouse IgG
1
κ, neutralizing 21125-1 50 µg Human IFN-αH IFNA14 —+—++ ——+——++
Human IFN-α MMHA-9 None Monoclonal mouse IgG
1
κ, neutralizing 21127-1 50 µg Human IFN-αI IFNA17 ++ ——+——++
Human IFN-α MMHA-14 None Monoclonal mouse IgG
1
κ, neutralizing 21129-1 50 µg Human IFN-αJ IFNA7 +++——
Human IFN-αK IFNA6 ++ —— +++ ++
Human IFN-α4b IFNA4 ++ ++ ++ +—++ ++
Human IFN-αWA IFNA16 — ++ — ++ —— + +
Human IFN-ω —— —
Human IFN-β —— — ——
Antigen Label Species/Isotype Catalog # Size
Human IFN-γ —— — ——
Human IFN-α None Polyclonal sheep serum, neutralizing 31100-1 1 x 10
5
NU
Bovine IFN-τ —— —
Human IFN-α None Polyclonal rabbit serum, neutralizing 31101-1 1 x 10
5
NU
Human IFN-α None Polyclonal rabbit serum, neutralizing 31130-1 2 x 10
4
NU
++ Binds Well
NU = Neutralization Unit
+ Binds Moderately Well
— Does Not Bind Well
www.interferonsource.com Tel: +1 732-777-9123
I
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