2008 PBL Cat_mech_r.qxd:PBL Catalog.mech 11/29/07 1:50 PM Page 9
Interferon
Human Interferon Alpha
PBL offers researchers a large selection of interferons of different the human interferon alpha sold for research use is IFN-αA (IFN-α2a) or
classes including multiple IFN-α subtypes. While there are numerous the closely related IFN-α2 (IFN-α2b). By testing and selecting specific
identified individual subtypes in the human interferon alpha family and alpha interferons to meet research needs, one may see differential
two commonly accepted naming conventions for the IFN-α subtypes activities that belie the subtypes’ true functions in vivo. The Human
(for more information, see chart on page 10), many of the subtypes Interferon Alpha Sampler helps researchers find the right IFN-αsubtype
display different plieotropic properties. Human interferon alpha A (IFN- for their research. The Sampler includes 20,000 units of each of twelve
αA) works reasonably well in most applications. Approximately 99% of interferon alpha subtypes. (Refer to PBL product #11001-1)
AMINO ACID DIFFERENCES BETWEEN HUMAN INTERFERON ALPHA SUBTYPES*
*These sequences are the mature,
secreted protein forms.
www.interferonsource.com Tel: +1 732-777-9123
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