natu-nov-15-07-p002_p054#242F03 9/11/07 13:53 Page 7
Hannover
Dresden
DFG Center for Regenerative Therapies Dresden (CRTD)
Based upon MHH’s recent key achievements and priorities, The Center for Regenerative Therapies in Dresden, at the city’s University of
REBIRTH’s focus is on developing regenerative technologies to treat Technology, was established in 2006 - following a competitive selection process - as
disorders of the blood (including immune disorders), and of the heart,
the German national research centre for regenerative therapies, funded by the
respiratory tract, liver and pancreatic beta cells. REBIRTH
German Research Foundation (DFG). In addition, the CRTD was awarded the
integrates excellent training with innovative science and both
prestigious ‘Cluster of Excellence’ status, making it the only such centre in the
experimental and clinical medicine. Intrinsic pathways and milieu-
former East Germany.
TLIGHT ON GERMANY
dependent mechanisms which control epigenetic reprogramming, cell
The aim and vision of the CRTD is to develop novel regenerative therapies for
expansion, differentiation, migration, organogenesis and disease-
widespread (and thus far incurable) diseases, such as Alzheimer’s, Parkinson’s and
diabetes. To accomplish this goal, the CRTD is taking an interdisciplinary SPO
specific regeneration are studied. Driven by these insights,
approach, integrating research in biomedical and materials sciences and
REBIRTH tests new approaches for regenerative therapies using nanotechnology, in order to produce therapies in the areas of haematology,
novel cell sources which are engineered by applying genetic, diabetes, neurodegenerative disease, bone and cartilage replacement, and
epigenetic, and scaffold-based principles. Expertise in various fields
cardiovascular research.
of engineering, chemistry, biophotonics and nanotechnology supports The CRTD network, which includes participants from outstanding research
and enhances these research and development activities. Finally, the
institutes and companies in Dresden, helps new regenerative therapies become
following also form an integral part of REBIRTH’s translational
reality. As the Centre’s Director, Professor Michael Brand, points out, “the unique,
activities: the existing wide range of certified/accredited facilities
international network structure of the CRTD, including over 80 research groups,
exemplifying good practice (laboratory, manufacturing and clinical);
allows the rapid transfer of new insights from basic research into clinical
application”. The new therapies will be developed in conjunction with commercial
close industrial collaborations; upscaling technologies; and pro-active
partners until they are market-ready. One initial success story has come from the
biosafety assessment. laboratory of new CRTD appointee Professor Ezio Bonifacio, where a Type 1
To promote young scientists and to connect research activities and
diabetes vaccination for children has been developed and will soon be going to
foster communication within the Cluster, REBIRTH has established
clinical trials. Another crucial element in the CRTD is its central technology
platform, making centrally-based, cutting-edge technology and expertise available
a PhD programme “Regenerative Sciences”, under the umbrella of
to the network and ensuring resources are used cost-effectively. A new, 38 million
the Hannover Biomedical Research School (HBRS), which was also euro, state-of-the-art building will help bring all the players together under the
successful in the Excellence Initiative of Germany as a Graduate same roof.
School. Promoting the careers of young scientists is an essential aspect of the CRTD’s
Please take note of the separate advertorial of the HBRS with its
work. As independent research associates or junior research group leaders,
PhD-Programs in this issue some pages forward.
talented young scientists are being given the opportunity to pursue their own
research ideas independently. Currently the CRTD houses nine such junior groups,
REBIRTH – Cluster of Excellence
but more groups will be established in the near future.
“From Regenerative Biology to Reconstructive Therapy” Visit our homepage for more informations:
http://www.crt-dresden.de
(Prof. Axel Haverich)
CRTD/DFG-Center for Regenerative Therapies Dresden –
Hannover Medical School
Cluster of Excellence
Carl-Neuberg-Str. 1
(Prof. Dr. Michael Brand)
D-30625 Hannover
Biotechnologisches Zentrum
Tatzberg 47/49
http://www.mh-hannover.de,
http://www.rebirth-hannover.de
D-01307 Dresden
W113569R W113570R
Berlin
In the BCRT, five medical research fields
Leipzig
Immune System
Cardiovascular System Translational Centre for Regenerative Medicine
Nervous System
Apply for Awards and Stipends:
Liver Therapy
Musculoskeletal System
Call for Applications Spring 2008
The TRM-Leipzig provides funds for investigator-initiated
are cross-linked by three research platforms translational awards that support young researchers as they pursue
Translational Technologies
their own diagnostics – or therapy-oriented concepts. New awards
Bio-Engineering
and stipends for doctoral students, postdocs and research fellows
Basic Research
early in their careers are available from 2009 onwards. Please visit
our homepage for more information. Throughout their funding
By integrating bio-engineering developments the BCRT
period, awardees will benefit from the Centre’s extensive
professional-development programme, covering both theory and
translates molecular as well as cell-based approaches
practice, through which it aims to build a cadre of translational
into novel regenerative therapies. The BCRT facilitates
researchers.
both pre-clinical and clinical studies with project
management supported by a central business
TEMAT, Tissue Engineering and Materials Science
development unit. CELLT, Cell Therapies for Repair and Replacement
7
REMOD, Regulatory Molecules and Delivery Systems
For information on vacant professorial positions
please refer to our website
IMONIT, Imaging, Modelling, and Monitoring of Regeneration
AND, Preclinical in vitro and in vivo Model Development in
v
ember 200
Berlin-Brandenburg Center for
GLP-conform facilities
RegenerativeTherapies W113571R
Translational Centre for Regenerative Medicine
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15 No
Charité-Universitätsmedizin Berlin
Universität Leipzig
Augustenburgerplatz 1, D-13353 Berlin, Germany,
Philipp Rosenthal Straße 55
JOBS
phone: +49 30 450 539 400, fax: +49 (0) 30 450 539 402
04103 Leipzig, Germany
contact@b-crt.de,
http://www.b-crt.de
http://www.trm.uni-leipzig.de/awards
TURE
W113573R
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