PioneeringNewTherapiesto toutilizethestate-of-the-art facilities developingandpursuingnewresearch
RestoreInsulinProduction
andexpertisetoquicklyandefficiently initiatives.Supportedbyprivate
TheInstituteisaninnovatorinseveral
evaluatepromisingnewresearch philanthropy,theDRIFoundationalso
researchareas;however,itsprinciplefocus
strategies.Muchofthisworkbegins fillsthegapsinmanystagesofthe
isthebiologicalreplacement ofinsulin
intheDRI’sFastTrackCenterfor researchprocessthat arenot covered
functiontorestorebloodsugarcontrol.
Testing,whereinvestigatorscanaccess bygrantsandotherfundingsources.
Knownforitsgroundbreakingwork
allthreeofthefundamentalphasesof
inislet transplantationresultingin
research–basic(inthelab),pre-clinical ACommunityResource
normalizedbloodsugarlevelsinstudy
(studymodels)andclinical(patient
AdesignatedCenterofExcellenceat
patients,theDRIisnowimproving
studies)–underoneroof.This
theUniversityofMiamiMillerSchoolof
transplant processesandaddressing
translationalapproachandstructure
Medicine,theDRIprovidesinformative
theremainingchallengesthat limit the
enablesresearcherstotakepotential
andpracticalContinuingMedical
procedure’swidespreadapplication.
newtherapiesbeguninthelaband
furtherdevelopthesetechniquesto
Educationprogramsforphysicians,
healthcareprofessionalsandindustry
Beyondislet transplantation,theDRI
benefit thosewithdiabetes.
representatives.Forpatientsandtheir
isopeningnewdoorstodiscoveryby
families,theDRI’sKosowDiabetes
developingnovelapproachestorestore
TheDRIappliesthissamecollaborative
naturalinsulinfunction.Scientistsfrom
approachasa trainingcenter,hosting
Treatment Centeroffersanarrayof
abroadrangeofdisciplinesareapplying
internationalconferencesand
diabetesmanagement andeducation
theirexpertiseby:
conductinghands–onworkshops
activities,aswellasparticipationin
forvisitingscientists.
clinicalresearchstudies,ensuringthe
highest standardsofhealthcaredelivery.
• constructingtissue-engineered
barriersandbiodevices;
TheInstitutealsofacilitatesthe
• generatingnew,smallmoleculesto
distributionofitsspecializedcell
TheBestHopeforaCure
eliminatetheneedforimmune-
processingequipment andotherdevices
Withanunwaveringcommitment to
suppressingdrugs;
toresearchersthroughout theworld.
curethosenowlivingwithdiabetes,along
• developingsophisticatedtechniques
Thisincludesthesystemthat separates
withitsuniquespirit ofcollaborationand
toassessislet viabilityandpredict
healthyinsulin-producingisletsfrom
fast trackapproachtoresearch,theDRI
long-termfunction;
adonorpancreas,whichwasinvented
isleadingtheinternationaleffort tocure
• transformingselect cellsofthebody
by theDRI’sscientificdirector,
thisdisease.Forthemillionsoffamilies
intoinsulin-producingcells;
Dr.CamilloRicordi.
affectedbydiabeteswhoarelookingto
theworldofscienceforanswers,the
• exploringmethodstoregenerate
isletswithinthenativepancreas.
ConsistentCompetitiveFunding
DRIisthebest hopeforacure.
DRIscientistshavebeenawarded
The Hub of a Global Research Alliance
competitivefederalandstategrantsfor
TheDRIhasalonghistoryofscientific
morethan30consecutiveyears.The
collaboration,but themost focusedand
resultingresearchfindingshavebeen
far-reachinginitiativetodateisthe
publishedextensivelyinpeer-reviewed
DiabetesResearchInstituteFederation.
journalsandtheDRI’smanyinnovations
Comprisedofadozenmedicalcenters
areusedindiabetescentersworldwide.
onalmost everycontinent,theDRI
Asleadersintheirfields,theInstitute’s
Federationisaninternational
facultyservesonnumerousnational
networkofleadingscientistswho
andinternationalcommittees,scientific
aresharingknowledge,applyingtheir
reviewpanelsandmedicalassociations
respectiveexpertisetokeyresearch
toprovideandinterpret scientificdata
areasandconcentratingsolelyon
andassist instrategicplanning.
curingthedisease.
Whilecompetitiveresearchgrantsare
TheInstitute’sopen-doorphilosophy
themainstayofworld-classresearch
providesopportunitiesforscientistsand
institutes,theDiabetesResearchInstitute
biomedicalcompaniesaroundtheworld
FoundationprovidestheDRIwith the
criticalseedfundingnecessaryfor
2007annualreport 7
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