Karolinska Institutet,Stockholm,Sweden University of Alberta,Edmonton,Canada
WithDr.P-OBerggren,theDRIhasestablishedaCellBiology CollaborationwithDr.G.Francis,forisolationandquantitation
andSignalTransductionProgramtodevelopmethodsofimaging ofoxidizedlipoprotein-associatedproteinsinnormaland
andmonitoringinsulin-producingcellsaftertransplantation. diseasestates.
Karolinska Institutet,Stockholm,Sweden University of Giessen Islet Transplant Center,Giessen,Germany
WithN.G.Larssononmitochondrialdiabetes. WithDr.M.Brendel,formalcollaborationtoestablishpilot
clinicalislet transplant protocols.
Karolinska Institutet,Stockholm,Sweden
WithS.Efendiconthedevelopment ofnewconceptsinthe University of Pavia,Italy
treatment oftype1andtype2diabetes. WithDr.E.Solciaonthestudyofhumanislet cellproliferation
inphysiologicalandpathologicalconditions.
Karolinska Institutet,Stockholm,Sweden
WithDr.R.Rieglerondetectionofsinglemoleculeeventsin University of Pavia,Italy
pancreaticß-cellsignaltransduction. WithDrs.P.DionigiandM.Alessianiontransplant biology
anddevelopment ofnewimmunosuppressiveprotocols.
The Krembil Family Epigenetics Laboratory,Center of
Addiction and Mental Health,Toronto,Ontario,Canada University of Pavia,Italy
WithDr.A.Petronistostudyepigeneticeffectsregulating WithDrs.F.LocatelliandD.Larizzaforthedevelopment of
theeffectsontheexpressionoftheinsulingene. immuneinterventionsfortype1diabetes.
Oxford Centre for Diabetes,Endocrinology and Metabolism, Universidade of São Paolo,Brasil
Oxford United Kingdom WithDr.J.Voltarellionimmuneinterventionsfortype1diabetes.
WithP.Rorsmanonpancreaticß-cellelectricalactivity.
Universidade of São Paolo,Instituto de Quimica,
Oxford University,Oxford,England,U.K (NUCEL) SP,Brasil
WithP.JohnsononcGMPislet cellprocessingand WithM.C.SogayaroncGMPcellprocessing/celltherapies.
transplantation.
University ofToronto,Toronto General Hospital,
San Raffaele Institute,Milano,Italy Toronto,Ontario Canada
WithM.G.Roncaroloonislet transplantationand WithD.J.Drucker,togenerateanexendin-4clonetoprotect
toleranceinduction. transplantedislets.
Stem Cells Argentina,Buenos Aires,Argentina Universität des Saarlandes,Homburg,Germany
Dr.E.Estrada,et.al,tostudy theeffectivenessofhyperbaric WithV.Flockerzi,investigationsontheroleofthe
oxygentherapyandautologousstemcellinfusionsonß-cell voltage-gatedcalciumchannel‚ß3subunit inpancreatic‚
regeneration.Additionalstudieswilladdressthemechanisms ß-cellsignaltransduction.
ofhyperbaricoxygentherapy.
University of Umeå,Umeå Sweden
Steno Diabetes Center,Genofte,Denmark WithDr.H.Edlund,DirectorofthePancreaticDevelopment and
WithT.Mandrup-Poulsenontheroleofcytokinesin ProgenitorCellBiologylaboratoryat theDRI.Onidentifyingthe
pancreaticß-celldeathintype1diabetes. criticalfactorsthat definethedevelopment ofinsulin-producing
vs.noninsulin-producingcellsofthepancreas,withspecial
Swiss Federal Institute ofTechnology (EPFL), emphasisplacedonthedevelopment ofß-cellsinparticular.
Lausanne,Switzerland
WithDr.J.Hubbellonnovelbioengineeringapproach Weizmann Institute of Science,Rehovot,Israel
forislet immmunoisolation. WithY.ReisnerandE.Freud(SchneiderChildren’sMedicalCenter)
toinvestigatethefunctionalefficacyofE42pigpancreatictissue
Tel Aviv University,Sackler School of Medicine,Tel Aviv,Israel tocurediabetesinnonhumanprimatesviatheimplantationof
WithDr.S.Efrat tostudytheimmunogenicityofartificial embryonicpancreatictissueinrhesusmonkeystodetermineif
ß-cells,whichmayrepresent aviablesourceoftransplantable afunctionalorgancan/willdevelop.
cellstoreversediabetes.
Weizmann Institute of Science,Rehovot,Israel
University of Alberta,Canada,Edmonton,Canada WithDr.M.Walkertocharacterizetranscriptionfactorsthat
WithJ.ShapiroonCITConsortiumstudies. regulateinsulingeneexpressionintolerogenicdendriticcells.
74 DIABETES RESEARCH INSTITUTE
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