Document: ADDIGEST_THERAPY_1ST_11-17-08_NOFOLIO13_B_T_13_42224;Page: 1;Trim size: (5.375 x 8.375 ");Plate: Composite;Date: 03 Nov, 2008 11:00:30
respiratory
“Thisconnection between[exercise-induced asthma]and secretionsmakes
sensebecause foryears one of themaintheoriespostulatedaboutEIA was
that it wasrelated to drying of theairwayswithexercise. This newstudy
builds upon this by provingthat people whohavefewer secretionsare more
likelytohaveEIA.”
—Dr. David Patterson, CommunityHealthNetwork
asthma.Most just don’twanttomakethe FEV1 was measured in volunteers without
factpublic.” asthma before andafter administering
methacholine,asubstance used to test for
increased airway responsiveness.Pilocarpine,Findings shed lightonEIA
an agentthatinducessweatingand saliva,In theSeptember issueofCHEST,the
then was dispensedpremierjournal
andmeasured.of theAmerican What your patients should know
Subjects whoCollegeofChest about exercise-induced asthma
experiencedthePhysicians,research
■ Exercisecaninduceanasthmaattackin greatest fall inshowed that
peoplewhohavenoothertriggersanddo FEV1 andwerecompetitiveathletes
notexperienceasthmaunderanyother affected theleast bywith EIAproduce
circumstances. thepilocarpine hadless sweat, tearsand
■ Peoplewithexercise-inducedasthmaare themost hyper-saliva than athletes
believedtobemorethanusuallysensitive reactive airways.withoutrespiratory
tochangesinthetemperatureand Asthma sufferersproblems.
humidityoftheair. hadsignificantly
“Thisconnection ■ Sportsorburstsofactivityfollowedby lowerlevelsofsweat
betweenEIA and briefrestperiodsareleastlikelytocause than thehealthy test
secretionsmakes asthmasymptoms. subjects.
sensebecause for ■ IndividualswithEIAtypicallyexperience So what do these
years oneofthe symptomswithinfiveto10minutesof findingsmean
main theories exercising,butsomepeoplehaveasthma to people with
postulated about symptomsonlywhentheystopexercising. EIA? According
EIAwas that it was to Patterson,
relatedtodrying physiciansnow will
of theairways have abetterideahow to treatEIA.
with exercise,” said Dr.David Patterson, “There aredrugs availabletopeoplewho
an allergist andclinicalimmunologist with have Sjogren’s syndrome,which is dryeyes
CommunityHealthNetwork.“This new anddry mouth, andthese drugsstimulate
studybuildsuponthisbyprovingthatpeople thesalivaryglandsinthe mouthtoproduce
whohavefewer secretionsare morelikelyto moresecretions,”Patterson said.“WhileI
have EIA.” am unawareofany drugsthatincrease
Dr.Warren Lockette,leadauthor of the airway secretionsortears, artificialtears
study, hadfluidsecretion ratesanalyzedin mightbehelpful.” ●
56 athletes suspectedofhavingEIA.The
FALL2008 •INDIANATHERAPISTSQUARTERLY 13
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