14 INGREDIENTS & ADDITIVES
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The levels of bound bacteria were determined in a means of stopping bacteria from entering host cells
microplate-based method specifically developed for this thereby preventing disease.”
purpose.
Bacterial adherence to host tissue is regarded as an he study highlights the potential of
important initial step for colonisation and infection.
The first adherence specificity ever recognised in
intestinal bacteria was binding to mannose-containing T
different food and feed components as
alternative binding matrices for
enteropathogens. However, the authors
receptors. Even today, the most common binding ability caution that careful interpretation of the adhesion
described with bacteria is mannose-directed adhesion. results is essential because of the magnitude of unknown
As the authors highlight in their paper, almost all factors involved, such as the expression of adhesins with
isolates of Ecoli, as well as other members of the a test strain, the relevance of the host in terms of an
Enterobactericeae, attach to mannose receptors by isolate’s niche, and the quality of the tested adhesion
means of proteinaceous appendages called fimbriae. matrix. In this context, consciousness of the fact that the
Other bacteria also possess different mannose-specific results were obtained with the products specified and
adhesins, too. treated as described is also important. In addition, only
Table 1 gives some examples of natural mannan one product sample was tested in each case.
sources that were included in this study. “Despite these reservations, the in vitro test proved
The results showed that sesame seed extract and highly sensitive and discriminating, and hence useful for
konjac gum had the greatest number of adhered the screening of a high number of products and
bacteria, leading to the conclusion that they may have a bacteria. The products that scored best, such as yeast
part to play in preventing certain E coli and Salmonella mannan- oligosaccharide, pumpkin, sesame seed extract,
from latching onto the host. palm kernel extract and konjac gum (against possibly
Becker added: “The importance of fibre, particularly zoonotic Salmonella), are worthy of further investigation
from certain foodstuffs, in maintaining a healthy gut and in more detail with a choice of different product batches
digestion cannot be underestimated. The study shows and selected bacteria, both in vitro and in vivo,” they
that these foods bind certain bacteria and may be a conclude. p
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