that we minimized the size of the tumor at the end of the therapy while having a bound
on the amount of inhibitors given. Here, the objective (2.5) incorporates this constraint
representing an alternative approach, which we will compare with the results of [6] and [5].
For simulation purpose in a later chapter, we will use mm3 for our measurements of p
and q volumes. Also,  = 0:084=day, b = 5:85=day, d = 0:00873=mm3=day, G = 0:15kg=mg
of dose/day and �nally  = 0:02=day: These values are taken from [3].
8
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