health management
Although research is still in In a recent US trial, scientists
the preliminary stages, discovered CoQ10 could be Market Summary
some scientists used as an alternative to
believe that toxic therapy for some The global CoQ10 sector was estimated
CoQ10 patients to be approximately 150 tons in 2005,
showing an increase of about 50% com-
pared with the year before. Back then,
the market for CoQ10 products had
already reached the $150 million mark
with in Japan — the spiritual home of the Q10
early stage revolution — with 35 metric tons of raw
myelodysplastic syn- material being consumed in the country.
has dromes (MDS) — thus spar- The overall requirement for CoQ10 is
the potential to ing patients the unpleasant side-ef- expected to double during the next
prevent or manage many fects that accompany toxic treatments. 5 years, and it is predicted that, world-
neurological conditions Andrew Weil, MD, founder and chairman wide, CoQ10 production will increase to
related to impaired energy production of the University of Arizona’s Program in 450 tonnes by 2009. Particularly strong
and oxidative stress, such as Alzheim- Integrative Medicine, believes chemo- growth is expected in the US, which has
er’s, Friedrich’s ataxia, Huntington’s therapy patients may benefit from daily a large consumer market for nutritional
disease and amyotrophic lateral CoQ10 supplements to help prevent supplements and is forecast to account
sclerosis (ALS). While many dispute damage to heart muscle that can occur for up to two thirds of global demand
such claims, further research is under with Adriamycin (doxorubicin).
way to determine CoQ10’s ability to en- The Nutrition Business Journal estimated
hance energy production and alleviate New studies suggest further benefits of CoQ10 sales in 2004 to be $283 million.
oxidative stress in ageing adults with supplemental CoQ10: Yet, another source cited “conserva-
neurodegenerative disorders. • Diabetes: Patients with type II diabe- tive” estimates that put worldwide sales
tes displayed improved blood sugar of CoQ10 at around $350 million in
Cancer control, reduced blood pressure and the same year. It is believed that these
New studies are highlighting the po- a lower haemoglobin A1C count, figures would have been considerably
tential of CoQ10 to avert melanoma, suggesting that CoQ10 may help to higher had they not been stemmed by
prostate and breast cancer. CoQ10’s prevent the metabolic complications availability issues. A further consequence
antioxidant and immune-enhancing of diabetes. of the supply issue was the soaring cost
properties may also benefit patients • Immune Response: People suffering of CoQ10. There are reports that on-the-
both during and after a course with hay fever, rhinitis and asthma- spot prices reached as high as $5000 per
of chemotherapy. Researchers in related allergies have decreased kilo at the height of the demand in 2005.
Italy recently discovered that CoQ10 blood levels of CoQ10. Supplements Yet, this lack of availability did not seem
levels in melanoma patients were could help to control the various to hinder launches of products containing
abnormally lower than in cancer-free allergic conditions. Likewise, HIV CoQ10: a total of 260 dietary supplement
participants. Levels were also signifi- patients can display reduced levels and skin care products containing CoQ10
cantly lower in melanoma patients of the nutrient, thus becoming are listed in Mintel’s GNPD as having
who developed metastases than in vulnerable to infection owing to launched in the United States between
metastasis-free patients. Measur- their weakened immune response. 2000 and September 2005 — and 75%
ing a patient’s CoQ10 levels may, A 200 mg daily dose of CoQ10 has of these were dietary supplements. Min-
therefore, help to determine whether been found to help improve the ratio tel’s European database, however, shows
a melanoma is likely to metastasize. of beneficial T-helper immune cells more use for CoQ10 in topical cosmetic
to detrimental T-suppressor immune products than in dietary supplements
Clinical tests in Spain have found cells. It could also help combat zid- (25% of the total 157 products listed for
that CoQ10 can arrest the growth of ovudine-associated muscle disease the same period).
malignant prostate cells without af- — a potential side-effect of the com-
fecting normal cells, while in Denmark, monly used HIV drug. For the consumer, the price varies
researchers treated 32 patients with • Eyesight: Patients with age-related according to dosage and brand; the
CoQ10 in conjunction with conventional macular degeneration have lower monthly cost for 100 mg per day is ap-
breast cancer therapy; six patients plasma CoQ10 levels than those with proximately $30 and for 1200 mg per
experienced partial tumour regression healthy vision. But adults in the early day is approximately $300.
and two saw a complete remission. stages who supplemented for a year
www.nutraceuticalmag.com may digital 2007 nutraceutical business & technology 25
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