health management
The Fall and Rise of
Coenzyme Q10
New research indicates the benefits of Coenzyme Q10 (CoQ10)
could far exceed previous expectations in the fight against disease.
Scientists have discovered that CoQ10, or ubiquinone, can help
prevent melanoma, endothelial dysfunction, cardiovascular disease
and photoageing. Results also indicate that the nutrient can slow
the progression of Parkinson’s disease, support immune health and
help preserve blood sugar levels in diabetics.
Coenzyme Q10 is a powerful antioxidant found naturally in all Endothelial Dysfunction
forms of animal life. It is synthesized in the membranes of hu- For years, scientists have known that by supporting energy
man cells with increased concentration in the heart because production in the heart tissues, CoQ10 may help congestive
of the high energy requirements of this cell type. The nutri- heart failure, high blood pressure, angina, arrhythmia and
ent plays a vital role in the production of chemical energy in mitral valve prolapse. Recent studies in Germany showed
mitochondria by participating in the production of adenosine improved endothelial function of the brachial artery in male
triphosphate (ATP) — the body’s ‘energy currency.’ Last year, patients after supplementation with CoQ10, thus guarding the
CoQ10 manufacturers struggled to meet demand when stud- cardiovascular system against a precursor to atherosclerosis.
ies revealed that the nutrient could help combat heart disease,
cancer and other age-related disorders. The latest findings An 8-year clinical trial of patients with cardiovascular disease
have led to another surge in demand for CoQ10 supplements found that CoQ10 helped improve their condition, with
as studies suggest that the vitamin could also alleviate condi- almost half demonstrating a decreased reliance on heart
tions such as migraine and periodontal disease, help maintain medications. Statin drugs, commonly used to treat high
healthy vision and improve fertility in men. cholesterol, can deplete levels of CoQ10. To counter this
deficiency, patients can supplement with CoQ10.
CoQ10 Applications
Whereas the US market uses the nutrient predominantly in the Neurodegenerative Diseases
treatment of cardiovascular and Parkinson’s disease, CoQ10 is Researchers at the University of California conducted a
featured more in cosmetics, beauty and skincare supplements randomized, placebo-controlled clinical trial to examine
in Europe and Japan. It has further uses as an antioxidant and CoQ10’s effects on slowing the functional decline brought
in combating the effects of ageing, but these applications are on by Parkinson’s disease. Patients who received 300 mg of
developing at a slower rate. CoQ10 demonstrated a 44% slower rate of decline compared
with the placebo group.
24 nutraceutical business & technology may digital 2007 www.nutraceuticalmag.com
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